Permanent Head Damage: PhD lessons learnt so far

There are things that I didn’t see coming when I started a PhD. Bearing in mind that I did a Master’s that was largely independent and certainly felt like a PhD, I was completely surprised how overwhelmed I felt starting out. I really am in a great environment filled with not only two highly experienced and motivating supervisors but a suite of senior scientists and post-docs that are exceptionally passionate about their trade. I can’t but help imagine what hell PhD must be for people who have none of these things, because truly, this is the hardest thing I have ever done.

As a bit of an overachiever and perfectionist, my experience of the transition to grad school was devastating. In undergrad it was easy to see that I was on the right track – get an A and you pretty much understand your work- but progress in higher degrees is very hard to gauge. Your positive reinforcements come from getting awards and grants and being asked to speak at conferences, for most of which you are competing with people who are seasoned professionals. So, you have to celebrate really tiny successes whenever they occur. I have learned to become overjoyed when controls work in an experiment and celebrate everyday my cells look happy. I’ve also learned that things will take at least 3 months longer than what is planned and am slowly learning to let go of things I can’t get done. Most importantly, I’ve started to see the light, and I’m pretty sure it’s not just my life going up in flames (although that is sometimes how it feels).

Dog fire
From http://weknowmemes.com/2014/09/this-is-fine-meme/

 

 

If you are just starting out, I’m going to throw you a bone. I am by no means a seasoned PhD candidate but I can reveal to you several pieces of advice about things no one really wants to talk about – especially in a world where saying you aren’t coping means you may have to cope with no funding.

  1. When fielding “how is your PhD going” questions from people who clearly don’t think that doing a PhD is a “real job”… I like to use unnecessarily big words. An example would be, “I am currently analysing the nuclear fission impact of a quark.” Having just bamboozled them, I can silently take joy in the knowledge I have no idea what I just said. Lesson one: don’t let people make you feel small or silly because you chose a difficult path.
  2. You will occasionally feel that a fog has settled and that “Keeping up with the Kardashians” is looking pretty good right now (a sad aside; Microsoft Word just autocorrected “Kardashians” for me).
  3. Sometimes my days feel like wading through molasses and others like running against Usain Bolt. Learning to cope with the pace of a doctorate can be daunting; try to stay organised. I use OneNote for everything and I feel comforted that my lab book and my hair appointments are all in one place.
  4. Everyone feels overwhelmed, but very few people will speak about it and its best to realise early that people don’t always want to. Some people would rather make strange barking noises in the corridor. But that’s ok too. People all cope in different ways and the good thing is that they are coping, so don’t knock them for the way they deal. Some people sink into a depression, which is scarily common (read this great article on the link between mental problems and academia).
  5. You will feel overcome with an occasional sense of disaster and that you will not make any difference to the world. The difference will be small, but it will be made. I call this stage Stage Impending Doom. This usually occurs around the time industry starts to look particularly wonderful- sometimes not even in the field you have studied. I have found myself wondering what it would be like to be a cashier in a clothing store.
  6. Dating isn’t easy. It never is. Very often the person you are dating will never do a PhD and doesn’t understand the magnetism of this stage of life. My personal opinion? Don’t make major life decisions during your PhD. But, on the flip side of that I have known many wonderful scientists who have planned weddings (sometimes married each other!) and had babies all while succeeding marvelously.
  7. If you don’t feel like throwing in the towel at some point, you are not normal. In fact they should just give you your PhD upfront. A very prominent scientist in my field asked me how many times I had quit my PhD once while socialising over finger foods at a conference. I gave him a puzzled look, “well….never.” He proceeded to tell me how he had quit 3 times. Perspective is an ironic beast.
  8. I feel guilty all the time. Out with friends? You should be writing. Going to gym? You should be writing. Having lunch? YOU SHOULD BE WRITING. You get the picture.

    dog science
    https://za.pinterest.com/pin/321514860871188497/
  9. Every once in a while you will have imposter syndrome where you feel you have no idea what you are doing. But remember: You belong there and you are not simply a Labrador holding a pipette.
  1. You have to learn not to take yourself too seriously. There is a fantastic website that oversimplifies PhD theses (An example; Actual title: Somatotopy of Second Order Lateral Line Projections in Larval Zebrafish. Simplified title: Fish are friends, not food. Until you inject them with rabies and then they’re neither). Give it a read and suddenly your project will really become great again.
  2. Having a great supervisor really is important. Yes, you are responsible for your thesis and work, but having an experienced ear that I can rely on has truly been the biggest blessing I’ve had so far. Navigating the murky waters of science politics is an unexpected terror I have frequently and having back-up is imperative.
  3. Be kind to those newer than you. Some newbies will come to compete with you, even though you have nothing to compete for. Try to be patient and don’t get swept up in this. Maybe they are just trying to gauge how good they are and they are struggling too.
  4. It is entirely possible to spend your stipend on snacks.
  5. It will be hard to watch your friends in different fields move on with their lives (houses, weddings, families) but your time will come, it will likely just take a bit longer.
  6. Always try to maintain perspective and to remember why it is that you wanted to do a PhD. Try not to forget that a PhD is pushing the boundary of all human knowledge. Quite frankly, I think we all need a standing ovation just for that.

 

The best piece of advice I have is that PhDs have been done by at least 15 million people on earth. You can do it too.

head case

If I were a plant pathogen, I would want to be a Phytophthora species

In the spirit of Saint Patrick’s Day (March 17), lets talk about Ireland. In many Christian denominations of Ireland, Saint Patrick’s Day is considered a feast day. However, ironically, I want to talk about the Irish potato famine.

Phytophthora infestans St Pattys

 

Why are there so many Irish communities around the world? Because nearly 25% of Ireland emigrated as a result of mass starvation caused by a plant disease in the mid 1800s. This disease, known as potato late blight, is caused by Phytophthora infestans.

 

Phytophthora is a Greek word that translates as ‘plant destroyer’ (phyto=plant, phthora=destroyer).

 

Phytophthora is the name of a genus or group of microorganisms that destroy plants by causing disease. Microorganisms that cause disease are referred to as plant pathogens. Pathogens in this group are responsible for many plant diseases around the world. For example, as mentioned previously, P. infestans already changed the history of the world, and is still causing issues today, even in South African potato and tomato fields.

Phytophthora species are causing many epidemics around the world. Five of the top 12 tree diseases in the UK are caused by Phytophthora species. One of these is also responsible for Sudden Oak Death in the United States—my first introduction to Phytophthora. Click here to see pictures from a recent excursion into Sudden Oak Death infected lands.

DSC_6061

Other notable Phytophthora diseases include Jarrah dieback in Australia, Kauri dieback in New Zealand, and Daño foliar de pino in South America.

Actually, the pathogen (Phytophthora ramorum) that causes Sudden Oak Death in the USA also causes ramorum blight in the UK, where it kills Japanese larch, an important timber species. One pathogen causing two major diseases on two continents! Both countries have spent millions trying to control the disease—not even counting the costs from damages, ecological impacts and increased regulations—yet South Africa may not even be looking out for it.

One species that is affecting South Africa is Phytophthora cinnamomi. This species, dubbed as the ‘biological bulldozer‘ in Australia, threatens South African proteas, orchards, vineyards and plantations. Even though this species is known to infect more than 2500 native species in Australia, we have a poor understanding of its impacts in fynbos here of South Africa.  This is one of the justifications for Cape Citizen Science, a research project focused on Phytophthora species in the Western Cape Province. You can contribute to this research and to the understanding of the impacts of Phytophthora cinnamomi by participating as a citizen scientist.

CankerSilverTree

Unfortunately, because Phytophthora species are microscopic, they are frequently (accidentally) spread around the world. I like to think we are getting better at stopping this from happening, but the reality is that more plant pathogens are introduced every year—frequently from the global trade of live plants, but also potentially from the soles of our hiking boots.

brasier

I can’t say what would happen if Phytophthora ramorum was introduced to South Africa (investigating this would be a cool research project), but after seeing the impacts of Sudden Oak Death first hand, I can say it is definitely worth watching out for. Hopefully if it is introduced, we can detected it early and eradicate it before it spreads too far to control, like it has in the UK and the USA. This is another justification for Cape Citizen Science. By reporting dying plants, you may be the first to detect a exotic and invasive Phytophthora species. The fynbos biome is immaculate because of the high amount of endemism—having many plant species that only exist here in South Africa.  Because of its incredible biodiversity, it is important to protect, and we can protect this biome by being on the look out for dying plants, reporting the ones that you come across. Cape Citizen Science is a platform for making these reports.

Even more scary than Phytophthora ramorum are the species that havn’t been discovered by science. It is estimated that between 200-500 species of Phytophthora are yet to be discovered. For example, oak trees started dying throughout California before Phytophthora ramorum was actually described and the origin of this pathogen still remains unknown. There are many Phytophthora species out there, some that may even be native to the fynbos biome. Identifying these species is another objective of Cape Citizen Science. By participating, you could be the first to collect a completely new species of Phytophthora.